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ReeCure

Multiple Sclerosis

Multiple sclerosis is an autoimmune disease that affects the brain and spinal cord (central nervous system).

Diseases Treatable by Stem Cells

1988 1
2008 200+
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Causes

Multiple sclerosis (MS) affects women more than men. The disorder most commonly begins between ages 20 and 40, but can be seen at any age.

MS is caused by damage to the myelin sheath, the protective covering that surrounds nerve cells. When this nerve covering is damaged, nerve impulses are slowed down or stopped. MS is a progressive disease, meaning the nerve damage (neuro degeneration) gets worse over time. How quickly MS progresses varies from person to person.

The nerve damage is caused by inflammation. Inflammation occurs when the body's own immune cells attack the nervous system. Repeated episodes of inflammation can occur along any area of the brain and spinal cord. Researchers are not sure what triggers the inflammation. The most common theories point to a virus or genetic defect or a combination of both.

People with a family history of MS and those who live in a geographical area with a higher incidence rate for MS have a higher risk of the disease.

Symptoms

Symptoms vary, because the location and severity of each attack can be different. Episodes can last for days, weeks or months. These episodes alternate with periods of reduced or no symptoms (remissions).

Fever, hot baths, sun exposure and stress can trigger or worsen attacks.

It is common for the disease to return (relapse). However, the disease may continue to get worse without periods of remission. As nerves in any part of the brain or spinal cord may be damaged, patients with multiple sclerosis can have symptoms in many parts of the body.

Muscle symptoms:
  • Loss of balance
  • Muscle spasms
  • Numbness or abnormal sensation in any area
  • Problems moving arms or legs
  • Problems walking
  • Problems with coordination and making small movements
  • Tremor in one or more arms or legs
  • Weakness in one or more arms or legs
Bowel and bladder symptoms:
  • Constipation and stool leakage
  • Difficulty beginning to urinate
  • Frequent need to urinate
  • Strong urge to urinate
  • Urine leakage (incontinence)
Eye symptoms:
  • Double vision
  • Eye discomfort
  • Uncontrollable rapid eye movements
  • Vision loss (usually affects one eye at a time)
Numbness, tingling or pain
  • Facial pain
  • Painful muscle spasms
  • Tingling, crawling or burning sensation in the arms and legs
Other brain and nerve symptoms:
  • Decreased attention span, poor judgement and memory loss
  • Difficulty reasoning and solving problems
  • Depression or feelings of sadness
  • Dizziness and balance problems
  • Hearing loss
Sexual symptoms:
  • Problems with erections
  • Problems with vaginal lubrication
Speech and swallowing symptoms:
  • Slurred or difficult-to-understand speech
  • Trouble chewing and swallowing
  • Fatigue is a common and bothersome symptom as MS progresses. It is often worse in the late afternoon.

Causes & Symptoms

Multiple sclerosis is an autoimmune disease that affects the brain and spinal cord (central nervous system).

Diseases Treatable by Stem Cells

1988 1
2008 200+
Not responding to Conventional Therapy? Fill out the form to find out how Stem Cells can work
Name

Email
 
Thank you for submitting the form.

Causes

Multiple sclerosis (MS) affects women more than men. The disorder most commonly begins between ages 20 and 40, but can be seen at any age.

MS is caused by damage to the myelin sheath, the protective covering that surrounds nerve cells. When this nerve covering is damaged, nerve impulses are slowed down or stopped. MS is a progressive disease, meaning the nerve damage (neuro degeneration) gets worse over time. How quickly MS progresses varies from person to person.

The nerve damage is caused by inflammation. Inflammation occurs when the body's own immune cells attack the nervous system. Repeated episodes of inflammation can occur along any area of the brain and spinal cord. Researchers are not sure what triggers the inflammation. The most common theories point to a virus or genetic defect or a combination of both.

People with a family history of MS and those who live in a geographical area with a higher incidence rate for MS have a higher risk of the disease.

Symptoms

Symptoms vary, because the location and severity of each attack can be different. Episodes can last for days, weeks or months. These episodes alternate with periods of reduced or no symptoms (remissions).

Fever, hot baths, sun exposure and stress can trigger or worsen attacks.

It is common for the disease to return (relapse). However, the disease may continue to get worse without periods of remission. As nerves in any part of the brain or spinal cord may be damaged, patients with multiple sclerosis can have symptoms in many parts of the body.

Muscle symptoms:
  • Loss of balance
  • Muscle spasms
  • Numbness or abnormal sensation in any area
  • Problems moving arms or legs
  • Problems walking
  • Problems with coordination and making small movements
  • Tremor in one or more arms or legs
  • Weakness in one or more arms or legs
Bowel and bladder symptoms:
  • Constipation and stool leakage
  • Difficulty beginning to urinate
  • Frequent need to urinate
  • Strong urge to urinate
  • Urine leakage (incontinence)
Eye symptoms:
  • Double vision
  • Eye discomfort
  • Uncontrollable rapid eye movements
  • Vision loss (usually affects one eye at a time)
Numbness, tingling or pain
  • Facial pain
  • Painful muscle spasms
  • Tingling, crawling or burning sensation in the arms and legs
Other brain and nerve symptoms:
  • Decreased attention span, poor judgement and memory loss
  • Difficulty reasoning and solving problems
  • Depression or feelings of sadness
  • Dizziness and balance problems
  • Hearing loss
Sexual symptoms:
  • Problems with erections
  • Problems with vaginal lubrication
Speech and swallowing symptoms:
  • Slurred or difficult-to-understand speech
  • Trouble chewing and swallowing
  • Fatigue is a common and bothersome symptom as MS progresses. It is often worse in the late afternoon.

Medical Tests

Symptoms of MS may mimic those of many other nervous system disorders. The disease is diagnosed by ruling out other conditions.

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People who have a form of MS called relapsing-remitting may have a history of at least two attacks, separated by a period of reduced or no symptoms.

The health care provider may suspect MS if there are decreases in the function of two different parts of the central nervous system (such as abnormal reflexes) at two different times. A neurological exam may show reduced nerve function in one area of the body or spread over many parts of the body.

This may include:
  • Abnormal nerve reflexes
  • Decreased ability to move a part of the body
  • Decreased or abnormal sensation
  • Other loss of nervous system functions
An eye examination may show:
  • Abnormal pupil responses
  • Changes in the visual fields or eye movements
  • Decreased visual acuity
  • Problems with the inside parts of the eye
  • Rapid eye movements triggered, when the eye moves
Tests to diagnose multiple sclerosis include:
  • Lumbar puncture (spinal tap) for cerebrospinal fluid tests, including CSF oligoclonal banding
  • MRI scan of the brain and MRI scan of the spine are important to help diagnose and follow MS
  • Nerve function study (evoked potential test)

Conventional Treatment

There is no known cure for multiple sclerosis at this time. However, there are therapies that may slow the disease. The goal of treatment is to control symptoms and help you maintain a normal quality of life.

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Medications used to slow the progression of multiple sclerosis are taken on a long-term basis.

Available Medications include:
  • Interferons (Avonex, Betaseron or Rebif), glatiramer acetate (Copaxone), mitoxantrone (Novantrone) and natalizumab (Tysabri) are approved for treating MS
  • Methotrexate, azathioprine (Imuran), intravenous immunoglobulin (IVIg) and cyclophosphamide (Cytoxan) may also be used if the above drugs are not working well

Steroids may be used to decrease the severity of attacks.

Treatments to control symptoms may include:
  • Medicines to reduce muscle spasms such as Lioresal (Baclofen), tizanidine (Zanaflex) or a benzodiazepine
  • Cholinergic medications to reduce urinary problems
  • Antidepressants for mood or behavior symptoms
  • Amantadine for fatigue
The following may help MS patients:
  • Physical therapy, speech therapy, occupational therapy and support groups
  • Assistive devices, such as wheelchairs, bed lifts, shower chairs, walkers and wall bars
  • A planned exercise program early in the course of the disorder
  • A healthy lifestyle, with good nutrition and enough rest and relaxation
  • Avoiding fatigue, stress, temperature extremes and illness

Household changes to ensure safety and ease in moving around the home are often needed.

Stem Cell Therapy

Numerous clinical trials are going on all over the world, including India using stem cells from various sources.

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We, at ReeCure offer you therapy using stem cells using our proprietary technology.

These stem cells could be of various types viz. Hematopoietic (CD 34+), Mesenchymal stem cells (MSCs) that are processed and isolated using Good Manufacturing (GMP) and Good Lab Practices (GLP) and in accordance with AABB standards. Stem cell therapy has helped numerous patients with Multiple Sclerosis lead more productive lives.

After years of extensive research and systematic compilation and collation of relevant data (through its research division), ReeLabs is now supremely confident of not only reversing the disease process of the affected patient but also improving the quality of life manifold. Stem cells produced by ReeLabs are completely safe, non-toxic, easy to administer and totally devoid of side effects with an excellent probability of homing and engraftment with parent cell, tissue or organ. The eminent panel of scientists and researchers at ReeLabs work exhaustively to design accurate treatment protocols that have yielded excellent results in most cases.

In nervous disorders like Multiple Sclerosis, where the cells that protect nerve fibers are lost, without a new source of functioning nerve tissue, no therapeutic possibilities exist. Perhaps the only hope for treating such individuals comes from the potential to create new nerve tissue restoring function from stem cells.

Stem cell therapy can help in patients with monoparesis (partial or incomplete paralysis affecting one or part of one extremity), mild hemiparesis (slight paralysis affecting one side of body) moderate ataxia, disturbing sensory loss, prominent urinary or eye symptom or a combination of lesser dysfunction. Stem cell therapy can help patients limited to a wheel chair to walk with support using braces or clutches.

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